IgE antibody levels to ingested soya protein determined in a normal adult population

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Abstract
Levels of soya protein-specific IgE were measured in a normal adult population (74 males, 15 females) who ingested soya-containing and control diets during 2 4-wk periods. Increases in soya-specific IgE were observed for some individuals following ingestion of the soya-containing diet; and for the female group, the increase in soya-specific IgE was statistically significant (P = 0.02). The increase of soya-specific IgE was small and led to lower levels than that associated with adverse effects. The increase in soya-specific IgE in the female group was accompanied by a significant increase (P = 0.02) in total IgA. Changes in the level of soya-specific hemagglutinating antibody, soya-specific IgG, IgA and IgM as measured by ELISA [enzyme-linked immunosorbent assay] and the immunoconglutinin titer could not be related to ingestion of the soya-containing diet.