Solution‐ and Solid‐Phase Synthesis of Radicicol (Monorden) and Pochonin C
- 9 August 2005
- journal article
- research article
- Published by Wiley in Chemistry – A European Journal
- Vol. 11 (17) , 4935-4952
- https://doi.org/10.1002/chem.200500160
Abstract
A modular synthesis for pochonin C and radicicol is reported. The two natural products were prepared in seven and eight steps, respectively, from three readily available fragments. Alternative syntheses of these compounds were achieved using a combination of polymer-bound reagents and solid phase reactions. The conformation of the two natural products was studied and compared by using 2D NMR spectroscopy.Keywords
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