Abnormal Purine and Pyrimidine Nucleotide Content in Primary Astroglia Cultures from Hypoxanthine—Guanine Phosphoribosyltransferase‐Deficient Transgenic Mice

Abstract
: Lesch‐Nyhan syndrome is a pediatric metabolic‐neurological syndrome caused by the X‐linked deficiency of the purine salvage enzyme hypoxanthine‐guanine phosphoribosyltransferase (HGPRT). ...

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