Abnormal Purine and Pyrimidine Nucleotide Content in Primary Astroglia Cultures from Hypoxanthine—Guanine Phosphoribosyltransferase‐Deficient Transgenic Mice
Open Access
- 1 March 1999
- journal article
- research article
- Published by Wiley in Journal of Neurochemistry
- Vol. 72 (3) , 1139-1145
- https://doi.org/10.1046/j.1471-4159.1999.0721139.x
Abstract
: Lesch‐Nyhan syndrome is a pediatric metabolic‐neurological syndrome caused by the X‐linked deficiency of the purine salvage enzyme hypoxanthine‐guanine phosphoribosyltransferase (HGPRT). ...Keywords
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