Ecotoxicological analysis of nostocyclamide, a modified cyclic hexapeptide from Nostoc

1 November 1996

journal article
Published by Taylor & Francis in Phycologia

Vol. 35 (sup6) , 183-188
https://doi.org/10.2216/i0031-8884-35-6s-183.1

Abstract

Ecotoxicological assays served to evaluate the inhibitory and toxic properties of the allelochemical nostocyclamide isolated from Nostoc. The purified molecule exhibited no inhibitory effects on the growth of Gram-negative and Gram-positive bacteria and Saccharomyces cerevisiae Meyer when applied in concentrations of up to 10 μM. In contrast, it significantly inhibited the growth of cyanobacteria at 0.1-μM and chlorophyceans at 1.0-μM concentrations. Against rotifers and crustaceans, nostocyclamide exhibited medium toxicity (about LC₅₀ 13 μM). The possible ecological role of this allelopathic compound is discussed.

Keywords

CYANOBACTERIA
SACCHAROMYCES CEREVISIAE
ROTIFERS
NOSTOCYCLAMIDE
ECOTOXICOLOGICAL ANALYSIS
CYCLIC HEXAPEPTIDE
MODIFIED CYCLIC

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