Detection of Mammaglobin mRNA in the Plasma of Breast Cancer Patients
- 1 September 2001
- journal article
- Published by Wiley in Annals of the New York Academy of Sciences
- Vol. 945 (1) , 192-194
- https://doi.org/10.1111/j.1749-6632.2001.tb03885.x
Abstract
It has been suggested that mammaglobin may be a useful marker for breast cancer clinical research. Studies investigating the detection of mRNA by RT‐PCR from circulating carcinoma cells in the peripheral blood of breast cancer patients have shown that mammaglobin is a highly specific marker and correlates with several prognostic factors, such as lymph node involvement. We aimed to detect cell‐free mammaglobin mRNA in the plasma of breast cancer patients and to investigate whether it can be used as a marker for diagnosis of breast cancer.Keywords
This publication has 3 references indexed in Scilit:
- Mammaglobin, a Breast‐Specific Gene, and Its Utility as a Marker for Breast CancerAnnals of the New York Academy of Sciences, 2000
- Mammaglobin Gene Expression: A Superior Marker of Breast Cancer Cells in Peripheral Blood in Comparison to Epidermal-Growth-Factor Receptor and Cytokeratin-19Laboratory Investigation, 2000
- Detection of Circulating Mammary Carcinoma Cells in the Peripheral Blood of Breast Cancer Patients Via a Nested Reverse Transcriptase Polymerase Chain Reaction Assay for Mammaglobin mRNAJournal of Clinical Oncology, 1999