Pulmonary Cineangiography in Experimental Chronic Hypoxia

Abstract
Guinea pigs were submitted to experimental chronic hypoxia in low pressure chambers. The pulmonary circulation was studied by the injection of radiopaque material in the anesthetized animal. The chronic hypoxic animals did have a decreased capillary bed visualization and an increased pulmonary transit time. Return to sea level atmospheres showed improvement, but residual lesions remained. The described alteration may be secondary to polycythemia and/or capillary lesions of the alveolar wall.