Toxicological Implications of Polymorphic Drug Metabolism
- 1 January 1980
- book chapter
- Published by Wiley
- Vol. 76, 219-244
- https://doi.org/10.1002/9780470720592.ch12
Abstract
This chapter contains section titled: Genetic Polymorphisms of Drug Metabolism Toxicological Implications of Polymorphic Drug Metabolism Genetic Polymorphism of Metabolic Oxidation Presystemic Metabolism of Drugs and Genetic Polymorphism of Oxidation Oxidation Phenotype and Alternative (Toxic) Pathway Metabolism Oxidation Phenotype and Metiamide-Induced Agranulocytosis References DiscussionKeywords
This publication has 42 references indexed in Scilit:
- Genetic evidence for the involvement of different oxidative mechanisms in drug oxidationJournal of Pharmacy and Pharmacology, 1979
- Interindividual and interspecies variation in the metabolism of the hallucinogen 4-methoxyamphetamineXenobiotica, 1979
- Hepatic First-pass Metabolism in Liver DiseaseClinical Pharmacokinetics, 1979
- Hypotensive response to debrisoquine and hydroxylation phenotypeLife Sciences, 1978
- Purification of UDP‐glucuronyltransferase from untreated rat liverFEBS Letters, 1977
- Cimetidine Therapy in a Patient with Metiamide-Induced AgranulocytosisNew England Journal of Medicine, 1977
- REVERSAL OF METIAMIDE-INDUCED AGRANULOCYTOSIS DURING TREATMENT WITH CIMETIDINEThe Lancet, 1975
- Effect of exposure to cigarette smoke on the metabolism of benzo6a9pyrene and acetophenetidin by lung and intestine of ratsToxicology and Applied Pharmacology, 1972
- Decreased Concentration of Phenacetin in Plasma of Cigarette SmokersScience, 1972
- Genetical studies on a new variant of serum cholinesterase detected by electrophoresisAnnals of Human Genetics, 1963