Non-synonymous Single Nucleotide Alterations Found in the CYP2C8 Gene Result in Reduced in Vitro Paclitaxel Metabolism.
- 1 January 2001
- journal article
- Published by Pharmaceutical Society of Japan in Biological & Pharmaceutical Bulletin
- Vol. 24 (12) , 1427-1430
- https://doi.org/10.1248/bpb.24.1427
Abstract
Japan's largest platform for academic e-journals: J-STAGE is a full text database for reviewed academic papers published by Japanese societiesKeywords
This publication has 11 references indexed in Scilit:
- Human liver carbamazepine metabolism: Role of CYP3A4 and CYP2C8 in 10,11-epoxide formationPublished by Elsevier ,2002
- Clinical Pharmacokinetics of CerivastatinClinical Pharmacokinetics, 2000
- Gene structure ofCYP2C8 and extrahepatic distribution of the human CYP2CsJournal of Biochemical and Molecular Toxicology, 1999
- Characterization of the cytochrome P450 enzymes involved in the in vitro metabolism of rosiglitazoneBritish Journal of Clinical Pharmacology, 1999
- Participation of CYP2C8 in retinoic acid 4-hydroxylation in human hepatic microsomesBiochemical Pharmacology, 1999
- Polymorphic human cytochrome P450 enzymes: an opportunity for individualized drug treatmentTrends in Pharmacological Sciences, 1999
- Genetic polymorphism of drug metabolizing enzymes: new mutations in CYP2D6 and CYP2A6 genes in Japanese.Pharmaceutical Research, 1998
- [16] Assays of CYP2C8- and CYP3A4-mediated metabolism of taxol in vivo and in vitroPublished by Elsevier ,1996
- Arachidonic acid metabolism by human cytochrome P450s 2C8, 2C9, 2E1, and 1A2: Regioselective oxygenation and evidence for a role for CYP2C enzymes in arachidonic acid epoxygenation in human liver microsomesArchives of Biochemistry and Biophysics, 1995
- Fluorescencein situ hybridization analysis of chromosomal localization of three human cytochrome P450 2C genes (CYP2C8, 2C9, and 2C10) at 10q24.1Journal of Human Genetics, 1994