Mechanism of voltage‐ and use‐dependent block of class A Ca2+ channels by mibefradil
Open Access
- 1 October 1998
- journal article
- Published by Wiley in British Journal of Pharmacology
- Vol. 125 (3) , 447-454
- https://doi.org/10.1038/sj.bjp.0702092
Abstract
1 The action of mibefradil was studied on wild type class A calcium (Ca2+) channels and various class A/L‐type channel chimaeras expressed in Xenopus oocytes. The mechanism of Ca2+ channel block b...Keywords
This publication has 25 references indexed in Scilit:
- A randomised, double-blind trial comparing mibefradil and amlodipine: two long-acting calcium antagonists with similar efficacy but different tolerability profilesJournal of Human Hypertension, 1997
- Pharmacologic and Therapeutic Differences Among Calcium Channel Antagonists: Profile of Mibefradil, a New Calcium AntagonistThe American Journal of Cardiology, 1996
- Transfer of High Sensitivity for Benzothiazepines from L-type to Class A (BI) Calcium ChannelsJournal of Biological Chemistry, 1996
- Transfer of L-type Calcium Channel IVS6 Segment Increases Phenylalkylamine Sensitivity of α1APublished by Elsevier ,1996
- Antihypertensive Properties of the Novel Calcium Antagonist Mibefradil (Ro 40-5967)Hypertension, 1996
- Effects of a new calcium antagonist, mibefradil (Ro 40–5967), on silent ischemia in patients with stable chronic angina pectoris: A multicenter placebo-controlled studyJournal of the American College of Cardiology, 1996
- Transfer of 1,4-Dihydropyridine Sensitivity from L-Type to Class A (BI) Calcium ChannelsNeuron, 1996
- Effects of Ro 40-5967, a Novel Calcium Antagonist, on Myocardial Function During Ischemia Induced by Lowering Coronary Perfusion Pressure in Dogs: Comparison with VerapamilJournal of Cardiovascular Pharmacology, 1989
- Primary Structure of the β Subunit of the DHP-Sensitive Calcium Channel from Skeletal MuscleScience, 1989
- In Vitro Pharmacologic Profile of Ro 40-5967, a Novel Ca2+ Channel Blocker with Potent Vasodilator but Weak Inotropic ActionJournal of Cardiovascular Pharmacology, 1989