Anterior poliomyelitis made its appearance in California in 1875, when 2 cases were observed near Eureka. The disease first became epidemic at La Grande, near San Francisco, in 1898. A second epidemic, of relatively few cases, followed in San Francisco in 1902. In 1912 the disease became epidemic in Southern California; 531 cases were reported with 129 deaths. Sporadic cases were reported from time to time until 1925, when the disease again became epidemic, with a total of 821 cases and 144 deaths. Two years later, 1,298 cases were reported, with 224 deaths. During the epidemic of 1930, 1,003 cases were reported, with 157 fatalities. The outbreak in 1934 showed a decided increase in the number of individual reported cases. This may have been due in part to the increasing alertness of the attending physicians, leading to a recognition of the disease in its preparalytic stage. A total of 3,333