Xenotransplantation and other means of organ replacement
- 1 November 2001
- journal article
- review article
- Published by Springer Nature in Nature Reviews Immunology
- Vol. 1 (2) , 154-160
- https://doi.org/10.1038/35100578
Abstract
Exciting new technologies, such as cellular transplantation, organogenesis and xenotransplantation, are thought to be promising approaches for the treatment of human disease. The feasibility of applying these technologies, however, might be limited by biological and immunological hurdles. Here, we consider whether, and how, xenotransplantation and various other technologies might be applied in future efforts to replace or supplement the function of human organs and tissues.Keywords
This publication has 66 references indexed in Scilit:
- Multilineage Cells from Human Adipose Tissue: Implications for Cell-Based TherapiesTissue Engineering, 2001
- NITRIC OXIDE-MEDIATED EXPRESSION OF Bcl-2 AND Bcl-xl AND PROTECTION FROM TUMOR NECROSIS FACTOR-??-MEDIATED APOPTOSIS IN PORCINE ENDOTHELIAL CELLS AFTER EXPOSURE TO LOW CONCENTRATIONS OF XENOREACTIVE NATURAL ANTIBODY1Transplantation, 2001
- Embryonic Stem Cell Lines Derived from Human BlastocystsScience, 1998
- ORTHOTOPIC HEART TRANSPLANTATION IN A TRANSGENIC PIG-TO-PRIMATE MODEL1Transplantation, 1998
- Transplantation of discordant xenografts: a challenge revisitedImmunology Today, 1996
- PROLONGED SURVIVAL OF DISCORDANT PORCINE ISLET XENOGRAFTS1Transplantation, 1996
- Xenotransplantation of pig kidneys to nonhuman primates: I. Development of the modelXenotransplantation, 1995
- Tolerance across discordant xenogeneic barriersXenotransplantation, 1995
- The control of homologous lysisImmunology Today, 1991
- Transplantation of discordant xenografts: a review of progressImmunology Today, 1990