Scientific foundation of mammographic screening is based on inconclusive research in Sweden

Abstract
EDITOR—In a letter Rosén and Rehnqvist criticised our analysis of mammographic screening in Sweden.1 We respond here to their criticism. The Swedish Board of Health and Welfare claims that mammographic screening has been shown to be effective in Swedish high quality clinical trials. A re-evaluation of these trials casts serious doubt on that conclusion. A meta-analysis of five Swedish clinical trials showed a significant 24% reduction in mortality from breast cancer, but the control groups in four of the …