Negative Interference in Cardiac Troponin I Immunoassays by Circulating Troponin Autoantibodies
Open Access
- 1 May 2005
- journal article
- Published by Oxford University Press (OUP) in Clinical Chemistry
- Vol. 51 (5) , 839-847
- https://doi.org/10.1373/clinchem.2004.040063
Abstract
Background: There are numerous potential sources of interference in immunoassays. Our aim was to identify the blood component that causes negative interference in cardiac troponin I (cTnI) immunoassays based on antibodies against the central part of cTnI.Keywords
This publication has 51 references indexed in Scilit:
- Towards a better understanding of heterophile (and the like) antibody interference with modern immunoassaysClinica Chimica Acta; International Journal of Clinical Chemistry, 2002
- Interference in immunoassay is an underestimated problemAnnals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2002
- Ability of Minor Elevations of Troponins I and T to Predict Benefit From an Early Invasive Strategy in Patients With Unstable Angina and Non-ST Elevation Myocardial InfarctionResults From a Randomized TrialJAMA, 2001
- Extensive Troponin I and T Modification Detected in Serum From Patients With Acute Myocardial InfarctionCirculation, 2000
- Myocardial infarction redefined—a consensus document of The Joint European Society of Cardiology/American College of Cardiology committee for the redefinition of myocardial infarctionJournal of the American College of Cardiology, 2000
- Present issues in the determination of troponins and other markers of cardiac damageClinical Biochemistry, 2000
- Biochemical Factors Influencing Measurement of Cardiac Troponin I in Serumcclm, 1999
- Interference in ImmunoassayAnnals of Clinical Biochemistry: International Journal of Laboratory Medicine, 1999
- False-Positive Troponin I in the MEIA Due to the Presence of Rheumatoid Factors in Serum: Elimination of This Interference by Using a Polyclonal Antisera Against Rheumatoid FactorsAmerican Journal of Clinical Pathology, 1999
- INTERFERENCES IN IMMUNOASSAYSPublished by Elsevier ,1996