Theoretical Calculation and Prediction of Caco-2 Cell Permeability Using MolSurf Parametrization and PLS Statistics
- 1 January 1997
- journal article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 14 (12) , 1786-1791
- https://doi.org/10.1023/a:1012196216736
Abstract
Purpose. To statistically model the permeability across Caco-2 cell monolayers using theoretically computed molecular descriptors and multivariate statistics. Methods. Seventeen structurally diverse...Keywords
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