Importance of Dietary Cholesterol in Man

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Abstract
The importance of dietary cholesterol in man has been reevaluated, using the formula diet technique. A prompt, significant increase in the serum cholesterol concentration occurred in all of 8 patients as the result of the feeding of a cholesterol formula diet. The discrepancies between this and previous studies is probably related to the administration of cholesterol in a form that facilitates its absorption. Substitution of corn oil for olive oil in the cholesterol-containing formula diet failed to prevent but did limit the increase in the level of serum cholesterol. Oral neomycin was found to prevent the increase in serum cholesterol resulting from the cholesterol-olive oil formula diet. It would seem pertinent that studies having to do with the prevention of coronary heart disease by diet give cognizance to the importance of dietary cholesterol.

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