Diltiazem and Reinfarction in Patients with Non-Q-Wave Myocardial Infarction
- 14 August 1986
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 315 (7) , 423-429
- https://doi.org/10.1056/nejm198608143150704
Abstract
We performed a multicenter, double-blind, randomized study to evaluate the effect of diltiazem on reinfarction after a non-Q-wave myocardial infarction. Nine centers enrolled 576 patients: 287 received diltiazem (90 mg every six hours) and 289 received placebo. Treatment was initiated 24 to 72 hours after the onset of infarction and continued for up to 14 days. The primary end point, reinfarction, was defined as an abnormal reelevation of MB creatine kinase in plasma within 14 days.Keywords
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