An epidemiological and genetic study of congenital profound deafness in Tunisia (governorate of Nabeul).
Open Access
- 1 January 1990
- journal article
- Published by BMJ in Journal of Medical Genetics
- Vol. 27 (1) , 29-33
- https://doi.org/10.1136/jmg.27.1.29
Abstract
An epidemiological and genetic study of profound deafness has been undertaken in the governorate of Nabeul in Tunisia. This paper deals with sensorineural deafness with no associated abnormalities. The prevalence was estimated to be 0.0007 and four clusters could be identified, two of which represent 51% and 34% respectively of the total number of cases. Segregation analysis performed in 29 pedigrees containing 415 subjects with 129 affected cases provided evidence for simple recessive inheritance with no sporadic cases.Keywords
This publication has 7 references indexed in Scilit:
- Studies on an Isolated West Indies PopulationNeuroepidemiology, 1987
- Studies on an isolated West Indies population: IV. Genetic study of hearing lossGenetic Epidemiology, 1986
- A UNIFIED MODEL FOR COMPLEX SEGREGATION ANALYSIS1983
- ESTIMATION OF PREVALENCE UNDER INCOMPLETE SELECTION.1965
- GENETIC TESTS UNDER INCOMPLETE ASCERTAINMENT1959
- Segregation Analysis in Human GeneticsScience, 1958
- Mathematical Methods for Population Genetics.Journal of the American Statistical Association, 1949