Bivariate Ratio Monitoring in Clinical Laboratories

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Abstract
The usefulness of monitoring bivariates was studied and discussed. Analysis of the correlation between bivariates demonstrated that combinations of bivariates can be divided into two groups. The first group was the combination in which a close correlation between two variates could be observed in any pathophysiologic state. The monitoring of the ratio of this first group was effective for the detection of analytical mistakes and the detection of symptom poor hereditary disorders, such as pharmacogenetical disorders. The second group was one in which a high correlation between two variates was obtained in some specific pathologic stage, and the monitoring the ratio of this second group gave high predictive values for the screening of that pathologic stage. It was demonstrated that the use of bivariate monitoring was not only very simple but also provided an effective laboratory data analysis system for the laboratory routine.

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