Involvement of CYP3A4 and CYP2D6 in the metabolism of haloperidol.
- 1 January 1997
- journal article
- Published by Springer Nature in Cellular and Molecular Neurobiology
- Vol. 17 (2) , 227-233
- https://doi.org/10.1023/a:1026317929335
Abstract
No abstract availableKeywords
This publication has 13 references indexed in Scilit:
- Determination of 4-(4-chlorophenyl)-4-hydroxypiperidine, a metabolite of haloperidol, by gas chromatography with electron-capture detectionJournal of Chromatography B: Biomedical Sciences and Applications, 1996
- Coadministration of fluvoxamine increases serum concentrations of haloperidol.1994
- MPP(+)-like neurotoxicity of a pyridinium metabolite derived from haloperidol: in vivo microdialysis and in vitro mitochondrial studies.1994
- Effect of quinidine on the interconversion kinetics between haloperidol and reduced haloperidol in humans: implications for the involvement of cytochrome P450IID6European Journal of Clinical Pharmacology, 1993
- High-performance liquid chromatographic method for the detection and quantitation of haloperidol and seven of its metabolites in microsomal preparationsJournal of Chromatography B: Biomedical Sciences and Applications, 1993
- Elevation of plasma concentrations of haloperidol after the addition of fluoxetineAmerican Journal of Psychiatry, 1991
- Oxidation of reduced haloperidol to haloperidol: involvement of human P450IID6 (sparteine/debrisoquine monooxygenase).British Journal of Clinical Pharmacology, 1991
- Identification of a potentially neurotoxic pyridinium metabolite of haloperidol in ratsBiochemical and Biophysical Research Communications, 1990
- Extrapyramidal symptoms in a patient taking haloperidol and fluoxetineAmerican Journal of Psychiatry, 1989
- Distribution, excretion and metabolism of neuroleptics of the butyrophenone type: Part I. Excretion and metabolism of haloperidol and nine related butyrophenone-derivatives in the Wistar ratEuropean Journal of Pharmacology, 1967