Immobilization of human thrombomodulin on glass beads and its anticoagulant activity
- 1 September 1992
- journal article
- research article
- Published by American Chemical Society (ACS) in Bioconjugate Chemistry
- Vol. 3 (5) , 363-365
- https://doi.org/10.1021/bc00017a002
Abstract
Human thrombomodulin (TM) was for the first time immobilized on glass beads by the reaction between the carboxyl group of TM and the amino group of glass beads using water-soluble carbodiimide. Immobilized human TM exhibited both anticoagulant activity and inhibition of platelet aggregation of human blood.Keywords
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