Effect of cortical implanatations of radioactive cobalt on learned behavior of rhesus monkeys.

Abstract
Irradiation of the cortex of the rhesus monkey by cobalt 60 placed at the surface of either the frontal or temporal lobe, delivering a dosage of either 8000 or 4000 r at 5 mm from the source, produces immediate total loss on delayed-response, two-trial discrimination, and crossed-strings tests. Recovery is gradual and progressive and is usually complete by 20 days from time of implantation. Surgical ablation immediately after irradiation of the area (which becomes necrotic from a 4000-r dose) does not prevent occurrences of the syndrome of learning loss and subsequent recovery.

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