Vitamin B12-binders in human body fluids. I. Antigenic and physico-chemical characteristics.
- 1 January 1969
- journal article
- Vol. 4 (1) , 125-40
Abstract
Three factors binding vitamin B12 are detected in human gastric juice by autoradiographs of immunoelectrophoresis. Binder 1 is present only in gastric juice and gastric mucosa extract and corresponds to intrinsic factor. Binder 2 is present also in other excretions such as bile, lactoserum, saliva, in serum and leucocyte extracts. Binder 3 present in saliva and gastric juice in lower quantity than binder 2, seems derived from this last one by attachment of sialic acid molecules.This publication has 29 references indexed in Scilit:
- Precipitating Serum Antibodies to Intrinsic Factor in Pernicious AnemiaActa Medica Scandinavica, 2009
- A Study of Precipitating Antibodies against Human Intrinsic FactorActa Medica Scandinavica, 2009
- Isolation of intrinsic factor and its probable degradation product, as their vitamin B12 complexes, from human gastric juiceBiochimica et Biophysica Acta (BBA) - General Subjects, 1966
- Isolation of Intrinsic Factors from Human Gastric Juice.Acta Chemica Scandinavica, 1965
- Effects of peptic digestion, pH change and heating on B12 binders in the electrophoretic partition of the human gastric juiceClinica Chimica Acta; International Journal of Clinical Chemistry, 1964
- Paper electrophoretic analysis of b12 binding in human gastric juiceClinica Chimica Acta; International Journal of Clinical Chemistry, 1964
- Immunoelectrophoresis of Human SalivaActa Medica Scandinavica, 1964
- Electrophoresis of Human Gastric JuiceNature, 1959
- INHIBITION OF INTRINSIC FACTOR BY PERNICIOUS ANÆMIA SERAThe Lancet, 1959
- INTRINSIC-FACTOR-INHIBITING SUBSTANCE IN SERUM OF ORALLY TREATED PATIENTS WITH PERNICIOUS ANÆMIAThe Lancet, 1958