Total Synthesis of (R)-(−)-β-Cuparenone
- 1 February 1989
- journal article
- research article
- Published by Taylor & Francis in Synthetic Communications
- Vol. 19 (3-4) , 679-688
- https://doi.org/10.1080/00397918908050715
Abstract
(R)-(−)-β-Cuparenone has been synthesized from (S)-(+)-acid-2 obtained via resolution of the racemic acid. Two of the noteworthy steps are (a) repeated methylation of ester (+)-8 with LDA/MeI to furnish (+)-10 and (b) the reaction of 12, having two neopentyl units with NaCN.Keywords
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