Abstract
Sodium saccharin in concentrations from 0.02-20.00 mg/ml inhibits the in vitro growth of glucose-grown cariogenic and other streptococci, and suppresses, especially at the higher concentration range, the fermentative acid production of these microorganisms to acid levels much lower than the critical pH of 5.5. These observations indicate a possible caries antagonism by saccharin. [Streptococcus mutans, S. mitis, S. salivarius, S. faecalis, S. faecalis var. liquefaciens, S. pyogenes, S. durans, S. agalactiae, S. lactis and S. sanguis were used.].

This publication has 0 references indexed in Scilit: