Outpatient oxygen therapy in chronic obstructive pulmonary disease. A review of 13 years' experience and an evaluation of modes of therapy

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Abstract
About 13 yr experience with home O2 for patients with advanced chronic obstructive pulmonary disease are reviewed. Home O2 is safe and relieves pulmonary hypertension and elevated RBC [red blood cell] mass in some, but not all patients. Marked clinical improvement is the most important result of long-term home O2 use, including reduced hospitalizations and return to gainful employment for a few patients. Chronic compensated CO2 retention is well tolerated and adaptive in cases of severe chronic airflow obstruction. New O2 concentrators are effective in correcting hypoxemia and may make home O2 administration more convenient and less expensive.