Facilitated Hexose Transporters: New Perspectives on Form and Function
- 1 August 2007
- journal article
- review article
- Published by American Physiological Society in Physiology
- Vol. 22 (4) , 234-240
- https://doi.org/10.1152/physiol.00011.2007
Abstract
The recent sequencing of the human genome has resulted in the addition of nine new hGLUT isoforms to the SLC2A family, many of which have widely varying substrate specificity, kinetic behavior, and tissue distribution. This review examines some new hypotheses related to the structure and function of these proteins.Keywords
This publication has 54 references indexed in Scilit:
- Cloning and functional characterization of the human GLUT7 isoform SLC2A7 from the small intestineAmerican Journal of Physiology-Gastrointestinal and Liver Physiology, 2004
- Structure and Mechanism of the Lactose Permease of Escherichia coliScience, 2003
- Core and surface mutations affect folding kinetics, stability and cooperativity in IL-1β: does alteration in buried water play a role?11Edited by C. R. MatthewsJournal of Molecular Biology, 2001
- Isosteric Replacement of Acidic with Neutral Residues in Extracellular Loop-2 of the κ-Opioid Receptor Does Not Affect Dynorphin A(1−13) Affinity and FunctionJournal of Medicinal Chemistry, 2000
- Alteration of Substrate Affinities and Specificities of theChlorella Hexose/H+ Symporters by Mutations and Construction of ChimerasPublished by Elsevier ,1998
- Functional Studies of Human GLUT5: Effect of pH on Substrate Selection and an Analysis of Substrate InteractionsBiochemical and Biophysical Research Communications, 1997
- Hydrogen Exchange and Protein Hydration: The Deuteron Spin Relaxation Dispersions of Bovine Pancreatic Trypsin Inhibitor and UbiquitinJournal of Molecular Biology, 1995
- A functional superfamily of sodium/solute symportersBiochimica et Biophysica Acta (BBA) - Reviews on Biomembranes, 1994
- Sequence and Structure of a Human Glucose TransporterScience, 1985
- THE MECHANISM OF SUGAR TRANSFER ACROSS ERYTHROCYTE MEMBRANESAnnals of the New York Academy of Sciences, 1972