Keeping the Gut Microflora at Bay
- 12 March 2004
- journal article
- editorial
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 303 (5664) , 1624-1625
- https://doi.org/10.1126/science.1096222
Abstract
The commensal microflora of the gut provide benefits to the host. They help to digest dietary carbohydrate and to maintain the appropriate balance among different microbial species so that the chance of gut colonization by pathogenic bacteria is reduced. In their Perspective, Kraehenbuhl and Corbett discuss new work (MacPherson and Uhr) that reveals how the host's mucosal immune response prevents commensal bacteria from straying beyond the gut mucosa where they might induce an unwanted systemic inflammatory immune response.Keywords
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