Bactericidal activity of vancomycin, daptomydn, ampicillin and aminoglycosides against vancomycin-resistant Enterococcus faecium

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Abstract
Daptomycin, vancomycin, ampicillin and aminoglycosides, alone or in combination, were tested for their bactericidal activity against 15 isolates of vancomycin-resistant Enterococcus faecium from immunocompromised children. The kill-kinetic studies at clinically achievable concentrations demonstrated that daptomycin alone or in combination with ampicillin had the greatest bactericidal activity