Na+,K+‐ATPase and Mg2+‐ATPase Activities in Different Regions of Rat Brain During Alloxan Diabetes
- 5 October 1982
- journal article
- research article
- Published by Wiley in Journal of Neurochemistry
- Vol. 39 (4) , 903-908
- https://doi.org/10.1111/j.1471-4159.1982.tb11475.x
Abstract
The effect of alloxan diabetes on the activities of Na+,K+-ATPase and Mg2+-ATPase was studied in three regions of rat brain at various time intervals after the onset of diabetes. It was observed that Na2+,K2+-ATPase activity increased at early time intervals after diabetes, followed by a recovery to near control levels in all three regions of the brain. There was an overall increase in Mg2+-ATPase activity in all the regions. A reversal of the effect was observed with insulin administration to the diabetic ratsKeywords
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