Maternal Inheritance of Atopy at the FcεRlβ Locus in Japanese Sibs
- 1 January 1997
- journal article
- research article
- Published by S. Karger AG in Human Heredity
- Vol. 47 (3) , 178-180
- https://doi.org/10.1159/000154409
Abstract
Twenty-four Japanese atopic sibs with asthma and/or rhinitis were tested for polymorphic microsatellite repeats of FcΕRIβ on chromosome 11q1.3. Significantly increased sharing of maternal alleles was found (χ2 = 5.86, p < 0.025) while no significant sharing was found for paternal alleles. These findings confirm maternal inheritance of atopy at this locus in a non-Caucasian population.Keywords
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