THE AMINO-ACID SEQUENCE OF EQUINE MILK LYSOZYME

  • 1 January 1985
    • journal article
    • research article
    • Vol. 10  (1) , 23-31
Abstract
The amino acid sequence of equine milk lysozyme was elucidated. The determination of the sequence of the N-terminal region of the whole protein, cyanogen bromide fragments, tryptic and chymotryptic peptides and fragments produced by chemical cleavage after Try residues were involved. The protein consists of a single chain of 129 amino acid residues and has a MW of 14647. While equine milk lysozyme has the essential features of a c(chick)-type lysozyme, there is only 51% sequence homology with human milk lysozyme and 50% with domestic hen egg white lysozyme. Some of the implications of the large number of differences are discussed.