Tumor-suppressor p53: implications for tumor development and prognosis.
- 1 September 1998
- journal article
- review article
- Published by American Society of Clinical Oncology (ASCO) in Journal of Clinical Oncology
- Vol. 16 (9) , 3158-3168
- https://doi.org/10.1200/jco.1998.16.9.3158
Abstract
The p53 protein plays a central role in modulating cellular responses to cytotoxic stresses by contributing to both cell-cycle arrest and programmed cell death. Loss of p53 function during tumorige...Keywords
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