Employment of Polyethylene Tubing for Production of Intra-Arterial Thrombi in Rabbits and Rats.

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Abstract
Arterial thrombi were produced in the aortae of rabbits and rats by insertion of specially fashioned polyethylene tube segments. These thrombi differ from clots formed in static blood in that they are relatively acellular precipitates containing fibrin and probably platelets. These thrombi eventually are organized and lead to plaques in which all elements of the initial thrombus are replaced by tissue from the intima. The resemblance of these plaques to the pearly white plaque frequently seen in the human aorta is striking.

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