A tri-armed sulfonamide host for selective binding of chloride

Abstract
An uncharged host 6 for selective binding of chloride is described. This host features a triazine–trione platform, three short side-arms which are conformationally preorganised relative to the platform, and p-nitrophenylsulfonamide groups for hydrogen-bonding to anions. Host 6 binds chloride with K ≈ 150 000 M−1 in CHCl3 and shows a chloride/nitrate selectivity of 102.

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