A trypanosome oligopeptidase as a target for the trypanocidal agents pentamidine, diminazene and suramin
Open Access
- 21 August 1998
- journal article
- research article
- Published by Wiley in FEBS Letters
- Vol. 433 (3) , 251-256
- https://doi.org/10.1016/s0014-5793(98)00914-4
Abstract
African trypanosomes contain a cytosolic serine oligopeptidase, called OP‐Tb, that is reversibly inhibited by the active principles of three of the five most commonly used trypanocidal drugs: pentami...Keywords
This publication has 38 references indexed in Scilit:
- Inhibition of Neutrophil Serine Proteinases by SuraminPublished by Elsevier ,1997
- Oligopeptidases, and the Emergence of the Prolyl Oligopeptidase FamilyBiological Chemistry Hoppe-Seyler, 1992
- Pentamidine concentrations in plasma, whole blood and cerebrospinal fluid during treatment of Trypanosoma gambiense infection in Côte d'IvoireTransactions of the Royal Society of Tropical Medicine and Hygiene, 1991
- Antiparasitic drug designParasitology Today, 1989
- Inhibition of Human Immunodeficiency Virus Type I Reverse Transcriptase by Suramin-related CompoundsJournal of General Virology, 1987
- Present status of chemotherapy and chemoprophylaxis of animal trypanosomiasis in the eastern hemispherePharmacology & Therapeutics, 1981
- Uptake of the trypanocidal drug suramin by bloodstream forms of Trypanosoma brucei and its effect on respiration and growth rate in vivoMolecular and Biochemical Parasitology, 1980
- Thiol Groups of Biological ImportancePublished by Wiley ,1951
- Neue Chemotherapeutika der 4‐Amino‐chinolin‐ReiheAngewandte Chemie, 1937
- 2. Bericht über die Prüfung von „Bayer 205” in Afrika1)Deutsche Medizinische Wochenschrift (1946), 1923