Incontinentia pigmenti. Evidence for both neutrophil and lymphocyte dysfunction
- 1 August 1978
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Dermatology
- Vol. 114 (8) , 1182-1186
- https://doi.org/10.1001/archderm.114.8.1182
Abstract
A child with incontinentia pigmenti (Bloch-Sultzberger syndrome) had recurrent pneumococcal meningitis and pneumococcal bacteremia with associated subdural hematomas. Immunologic evaluation revealed defective neutrophil chemotaxis with normal neutrophil chemiluminescense. Lymphocytes showed a depressed proliferative response to phytohemagglutinin stimulation. An immunologic defect may prove to be part of this syndrome.This publication has 6 references indexed in Scilit:
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- Disorders of phagocyte functionArchives of Dermatology, 1976
- Infection, dermatitis, increased IgE, and impaired neutrophil chemotaxis. A possible relationshipArchives of Dermatology, 1976
- Incontinentia pigmenti: a chromosomal breakage syndromeJournal of Heredity, 1976
- Retinoblastoma in Bloch-Sulzberger SyndromeOphthalmologica, 1976
- Defective Neutrophil Chemotaxis and Cellular Immunity in a Child with Recurrent InfectionsAnnals of Internal Medicine, 1973