Enhanced Expression of the Homeostatic Chemokines CCL19 and CCL21 in Clinical and Experimental Atherosclerosis
- 1 March 2007
- journal article
- research article
- Published by Wolters Kluwer Health in Arteriosclerosis, Thrombosis, and Vascular Biology
- Vol. 27 (3) , 614-620
- https://doi.org/10.1161/01.atv.0000255581.38523.7c
Abstract
Objective— Based on their role in T-cell homing into nonlymphoid tissue, we examined the role of the homeostatic chemokines CCL19 and CCL21 and their common receptor CCR7 in coronary artery disease... We show increased plasma levels of the homeostatic chemokines in CCL19 and CCL21 in clinical and experimental atherosclerosis. By promoting inflammatory responses in T-cells and by inducing a matri...Keywords
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