The Treatment of Angina Pectoris

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Abstract
The NitritesThe nitrites are among the oldest drugs advocated for the prophylactic treatment of angina pectoris. Field,4 in 1858, reported on the prophylactic and therapeutic value of nitroglycerin in 1 patient with all the symptoms of angina pectoris, although Murrell5 is generally given credit for recommending its use routinely in 1879 for this condition. Bradbury,2 in 1895, first prepared erythrol tetranitrate and mannitol hexanitrate (among others in this series of alcohols) and advised their use as vasodilators. Pentaerythritol tetranitrate and triethanol amine trinitrate, like those mentioned above, have been well known for years as explosives, but have been advocated . . .