Intrathecal ketamine reduces morphine requirements in patients with terminal cancer pain

1 April 1996

journal article
clinical trial
Published by Springer Nature in Canadian Journal of Anesthesia/Journal canadien d'anesthésie

Vol. 43 (4) , 379-383
https://doi.org/10.1007/bf03011718

Abstract

Ketamine has been administered epidurally and intrathecally for operative and post-operative pain control. Animal studies showed potentiation of analgesia induced by ketamine and morphine. We hypothesized that intrathecal ketamine would potentiate the effects of intrathecal morphine in the treatment of cancer pain.

Keywords

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