Identification of desmethyl metabolite of sulfadimethoxine in chicken excreta.
- 1 January 1986
- journal article
- research article
- Published by Japanese Society of Veterinary Science in The Japanese Journal of Veterinary Science
- Vol. 48 (5) , 999-1002
- https://doi.org/10.1292/jvms1939.48.999
Abstract
An unknown metabolite of sulfadimethoxine (SDM) in chicken excreta was identified as N1-(2-methoxy-6-hydroxy-4-pyrimidinyl) sulfanilamide by mass spectrometry, infrared spectroscopy, and etc. It was found to be a principal metabolite in the excreta of chicken that received SDM and considered as the causal substance of the nonlinear pharmacokinetics of SDM in chicken. This is the first report, in which the compound is identified as the major metabolite of SDM.This publication has 1 reference indexed in Scilit:
- Mechanisms of nonlinear pharmacokinetics of sulfadimethoxine in cocks.The Japanese Journal of Veterinary Science, 1986