Adenovirus-Antibody Agglutination Reactions
Open Access
- 1 November 1965
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Immunology
- Vol. 95 (5) , 810-817
- https://doi.org/10.4049/jimmunol.95.5.810
Abstract
Summary: Adenovirus particles agglutinate in the presence of optimal proportions of type-specific antisera. Reactions can be visualized either by electron microscopy or, if virus concentrations are sufficiently high, in test tubes with the unaided eye. Virus-antibody complexes are characteristically leaf-like, and are usually composed of only one layer of particles. The width of the fringe (probably antibody molecules) surrounding particles after reaction with antiserum averaged 33 mµ. Agglutination cross-reactions occur between adenovirus types 12 and 18, but other adenoviruses tested (types 1, 2, 3 and 7) agglutinate only with their own antiserum.This publication has 1 reference indexed in Scilit: