Enhancing the effectiveness of relaxation^thermal biofeedback training with propranolol hydrochloride.
- 1 January 1995
- journal article
- clinical trial
- Published by American Psychological Association (APA) in Journal of Consulting and Clinical Psychology
- Vol. 63 (2) , 327-330
- https://doi.org/10.1037//0022-006x.63.2.327
Abstract
This article evaluated the ability of propranolol to enhance results achieved with relaxation-biofeedback training. Thirty-three patients were randomized to relaxation-biofeedback training alone (administered in a limited-contact treatment format), or to relaxation-biofeedback training accompanied by long-acting propranolol (with dosage individualized at 60, 120, or 180 mg/day). Concomitant propranolol therapy significantly enhanced the effectiveness of relaxation-biofeedback training when either daily headache recordings (79% vs. 54% reduction in migraine activity) or neurologist clinical evaluations (90% vs. 66% reduction) were used to assess treatment outcome. Concomitant propranolol therapy also yielded larger reductions in analgesic medication use and greater improvements of quality of life measures than relaxation-biofeedback training alone but was more frequently associated with side effects.Keywords
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