Effects of Continuous Low-Level Cobalt-60 Gamma Radiation on an in Vitro Mammalian Cell System: I. Response to Varying Dose Rates

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Abstract
A system has been developed, with mammalian cells grown in vitro, which provides a method for the rapid detection and quantitation of continuous low -level radiation effects. There is a linear relationship between the dose rate and the changes in generation time of the irradiated cultures. Possible mechanisms of chronic radiation action are discussed in light of acute radiation data, and the results concerning chronic radiation are presented.