Mixed Infection of a Bacterium with Coli-Dysentery Phage T5 and a Serologically Related Salmonella Phage

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Abstract
A comparison of closely related viruses will serve to distinguish those hereditary properties which are capable of undergoing change or mutation. Studies of this kind should eventually increase our understanding of the basic phenomena leading to the evolution of new viral types. There is evidence that serological relationship in viruses is correlated with similarity in other properties, as is seen in the lymphogranuloma-psittacosis group. Therefore, search was instituted for additional viruses serologically related to one or another member of the T group of coli-dysentery phages. This paper is a report of the properties of a bacterial virus attacking Salmonella paratyphi B (S. schottmuelleri) and a comparison with the corresponding properties of a serologically related virus, coli-dysentery phage T5. Materials and Methods. Bacteriophage T5 and its host cell, Escherichia coli strain B, have been described by Demerec and Fano (1). The phage attacking S. paratyphoid B was obtained from Dr. I. N.

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