Efficient synthesis of the nonamannoside residue of high mannose glycoproteins
- 1 June 2005
- journal article
- Published by Canadian Science Publishing in Canadian Journal of Chemistry
- Vol. 83 (6-7) , 693-701
- https://doi.org/10.1139/v05-066
Abstract
An efficient synthesis of the nonamannoside residue 1 of high mannose glycoproteins was achieved using an oligomer-supported solution synthesis with low-molecular-weight polyethylene glycol as the anchor. The synthesis required only five coupling steps from only two monosaccharide building blocks with an overall yield of 12%.Key words: nonamannoside, oligosaccharide synthesis, soluble polymer support synthesis, glycoproteins.Keywords
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