Bone Formation and Destruction in Hyperostoses Associated with Meningiomas

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Abstract
The bone growth and destruction which is seen in hyperostoses of the skull associated with meningiomas is a function of the tumor cells. Such cells can produce fibroblasts, osteoblasts and os-teoclasts, or act as the latter 2 without apparent morphologic alteration. The local invasiveness of meningiomas is demonstrated by their growth into the diploe and haversian canals of the adjacent skull.

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