Induction of peroxisomal β-oxidation in rat liver by high-fat diets
- 15 January 1980
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 186 (1) , 369-371
- https://doi.org/10.1042/bj1860369
Abstract
Liver peroxisomes were prepared by using a Percoll gradient in a vertical rotor. .beta.-Oxidation was measured in peroxisomes isolated from livers of rats fed on either high- (15% by wt) or low- (5% by wt) fat diets. The feeding of high-fat diets gave a 1.4- to 2.4-fold increase in total liver peroxisomal .beta.-oxidation, and a similar increase in specific activity. A 1.5- to 4.5-fold increase was seen in the specific activity of purified peroxisomal preparations. The reasons for these increases are discussed.This publication has 9 references indexed in Scilit:
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