BLOOD CHEMICAL CHANGES IN BOECK'S SARCOID WITH PARTICULAR REFERENCE TO PROTEIN, CALCIUM AND PHOSPHATASE VALUES

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Abstract
Blood chemistry studies on 11 patients are presented. Hyperglobulinemia and hyper-proteinemia persisted over periods of yrs. in active cases and disappeared in 2 healed cases. The serum Ca and blood phosphatase were elevated with the blood P and non-protein N values normal. Blood cholesterol was low or normal with esters averaging 64% in active cases. Ca tolerance tests gave variously shaped curves. Bence-Jones protein was found twice in the urine without bone lesions. Bilirubin tolerance tests showed retention in 4 cases. This with the elevated phosphatase and fractional precipitation patterns of the serum proteins indicated impaired hepatic function. The cystic changes found occasionally in the bones were not associated with hyperparathyroidism.

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