BIOTIN METABOLISM IN PLANTS
- 1 June 2000
- journal article
- Published by Annual Reviews in Annual Review of Plant Biology
- Vol. 51 (1) , 17-47
- https://doi.org/10.1146/annurev.arplant.51.1.17
Abstract
Biotin is an essential cofactor for a small number of enzymes involved mainly in the transfer of CO2 during HCO-3-dependent carboxylation reactions. This review highlights progress in plant biotin research by focusing on the four major areas of recent investigation: the structure, enzymology, and localization of two important biotinylated proteins (methylcrotonoyl-CoA carboxylase involved in the catabolism of leucine and noncyclic isoprenoids; acetyl-CoA carboxylase isoforms involved in a number of biosynthetic pathways); the biosynthesis of biotin; the biotinylation of biotin-dependent carboxylases, including the characterization of biotin holocarboxylase synthetase isoforms; and the detailed characterization of a novel, seed-specific biotinylated protein. A central challenge for plant biotin research is to determine in molecular terms how plant cells regulate the flow of biotin to sustain the biotinylation of biotin-dependent carboxylases during biosynthetic reactions.This publication has 169 references indexed in Scilit:
- Acetyl-CoA carboxylase exerts strong flux control over lipid synthesis in plantsPublished by Elsevier ,2002
- The pea chloroplast membrane‐associated protein, IEP96, is a subunit of acetyl‐CoA carboxylaseThe Plant Journal, 1996
- Recent advances in the biosynthesis of plant fatty acidsBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1996
- Induction of β‐methylcrotonyl‐coenzyme A carboxylase in higher plant cells during carbohydrate starvation: evidence for a role of MCCase in leucine catabolismFEBS Letters, 1996
- Prediction of the three‐dimensional structures of the biotinylated domain from yeast pyruvate carboxylase and of the lipoylated H‐protein from the pea leaf glycine cleavage system: A new automated method for the prediction of protein tertiary structureProtein Science, 1993
- Cloning and characterization of the Bacillus sphaericus genes controlling the bioconversion of pimelate into dethiobiotinGene, 1990
- A gene induced by the plant hormone abscisic acid in response to water stress encodes a glycine-rich proteinNature, 1988
- Inhibition of plant acetyl-coenzyme a carboxylase by the herbicides sethoxydim and haloxyfopBiochemical and Biophysical Research Communications, 1987
- Evidence for distinct 3-methylcrotonyl-CoA and geranyl-CoA carboxylases in Pseudomonas citronellolisBiochemical and Biophysical Research Communications, 1976
- Evidence for the enzymic defect in β‐methylcrotonylglycinuriaFEBS Letters, 1973