Bovine lactoferricin causes apoptosis in Jurkat T-leukemia cells by sequential permeabilization of the cell membrane and targeting of mitochondria
- 1 July 2007
- journal article
- Published by Elsevier in Experimental Cell Research
- Vol. 313 (12) , 2634-2650
- https://doi.org/10.1016/j.yexcr.2007.05.015
Abstract
No abstract availableKeywords
Funding Information
- Nova Scotia Health Research Foundation
- Canadian Institutes of Health Research
- Natural Sciences and Engineering Research Council of Canada
- Leukemia and Lymphoma Society of Canada
- Dairy Farmers of Canada
- Canadian Cancer Society
This publication has 43 references indexed in Scilit:
- The antimicrobial peptide, lactoferricin B, is cytotoxic to neuroblastoma cells in vitro and inhibits xenograft growth in vivoInternational Journal of Cancer, 2006
- Bovine lactoferricin selectively induces apoptosis in human leukemia and carcinoma cell linesMolecular Cancer Therapeutics, 2005
- Interactions of lactoferricin-derived peptides with LPS and antimicrobial activityFEMS Microbiology Letters, 2004
- The antimicrobial peptides lactoferricin B and magainin 2 cross over the bacterial cytoplasmic membrane and reside in the cytoplasmFEBS Letters, 2001
- Three-Dimensional Solution Structure of Lactoferricin B, an Antimicrobial Peptide Derived from Bovine LactoferrinBiochemistry, 1998
- Lactoferricin of Bovine Origin is More Active than Lactoferricins of Human, Murine and Caprine OriginScandinavian Journal of Infectious Diseases, 1998
- Apoptosis in Human Leukemic Cells Induced by Lactoferricin, a Bovine Milk Protein-Derived Peptide: Involvement of Reactive Oxygen SpeciesBiochemical and Biophysical Research Communications, 1997
- Lactoferrin: Molecular Structure and Biological FunctionAnnual Review of Nutrition, 1995
- Antibacterial spectrum of lactoferricin B, a potent bactericidal peptide derived from the N‐terminal region of bovine lactoferrinJournal of Applied Bacteriology, 1992
- Identification of the bactericidal domain of lactoferrinBiochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1992